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Medchemexpress LLC Boc-N-Amido-PEG4-propargyl | 1219810-90-8 | 99.7% | C16H29NO6 | 100 MG
Supplier: Medchemexpress LLC HY140879100MG
Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs themselves contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase, and the other for the target protein, enabling PROTACs to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
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