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Medchemexpress LLC Boc-N-Amido-PEG4-propargyl | 1219810-90-8 | 99.7% | C16H29NO6 | 250 MG
Supplier: Medchemexpress LLC 250MGHY140879
Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing an Alkyne group that enables it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs themselves are designed with two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other targets the protein of interest, utilizing the intracellular ubiquitin-proteasome system for selective protein degradation.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
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