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Medchemexpress LLC Boc-NH-PEG1-CH2COOH | 142929-49-5 | 98.0% | C9H17NO5 | 1 G
SDP

Supplier:  Medchemexpress LLC HY1404761G

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Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

  • Molecular weight: 219.23
  • Appearance: Solid-liquid mixture
  • Color: Colorless to light yellow
  • SMILES: O=C(O)COCCNC(OC(C)(C)C)=O
  • Storage (pure form): -20°C for 3 years, 4°C for 2 years
  • Storage (in solvent): -80°C for 6 months, -20°C for 1 month
  • Solubility (in vitro): DMSO at 100 mg/mL (456.14 mM)
  • Solubility (in vivo): Protocols available for DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil

Catalog No. 50-003-53066


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