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Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 50 G
Supplier: Medchemexpress LLC HYW00505650G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are composed of two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs utilize two ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase
- Other ligand binds to the target protein
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- High solubility in DMSO (100 mg/mL)
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