Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC Boceprevir 394730-60-0 5mg
Supplier: Apexbio Technology LLC A32615
Boceprevir is an oral inhibitor targeting hepatitis C virus (HCV) NS3 protease an enzyme essential for processing viral polyproteins during HCV replication The compound binds directly and reversibly to the NS3 enzyme s active site forming a covalent adduct through its ketoamide functionality Cell-based replicon assays demonstrated that boceprevir inhibits HCV replication in cultured hepatocytes with an IC90 of approximately 350 nM In preclinical studies boceprevir exhibited favorable selectivity towards HCV NS3 relative to human neutrophil elastase Commonly boceprevir is used in research investigating HCV replication mechanisms and NS3 enzyme function as well as in antiviral combination assays involving interferon-based regimens
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?