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Sigma Aldrich Bocnh-Peg4-Acid

Catalog No. 9025511G Shop All MilliporeSigma Sigma Organic Chemistry Products
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90-255-11G 50 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC™ molecules) for targeted protein degradationA Hexylchloride-Based Catch-and-Release System for Chemical Proteomic ApplicationsA Biocompatible Condensation Reaction for the Labeling of Terminal Cysteine Residues on ProteinsPROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Specifications

CAS 1835705-57-1
Molecular Formula C32H47ClN4O6S
Linear Formula C32H47ClN4O6S
MDL Number MFCD31560480
Quantity 50 mg
Synonym 2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid; Boc-NH-PEG4-CH2COOH
Molecular Weight (g/mol) 651.26 g/mol
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