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Echelon Biosciences Research Labs BODIPY FL-PI(3,4)P2 100 ug
Supplier: Echelon Biosciences Research Labs C34F6100UG
(BODIPY FL Phosphatidylinositol 3,4-bisphosphate) is a water soluble analog of PI(3,4)P2 labeled with the green fluorophore, Bodipy-FL at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions. This item is non returnable
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