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Selleck Chemical LLC Bosutinib (SKI-606) 10mg 380843-75-4
Supplier: Selleck Chemical LLC S101410MG
Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERK and JAK/STAT3 signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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