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Invitrogen™ Bovine Protein C Native Protein

Catalog No. PIRP43085
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100 μg
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Catalog No. Quantity
PIRP43085 100 μg
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Catalog No. PIRP43085 Supplier Invitrogen™ Supplier No. RP43085
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Description

Native Protein

RP-43085 contains native bovine Protein C protein. RP-43085 may be used as a positive control in many immunological assays.

Protein C is a vitamin K-dependent plasma glycoprotein that is cleaved to its activated form by the thrombin-thrombomodulin complex. Protein C in its activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Protein C is a vitamin K-dependent serine protease produced in the liver and made up of 2 polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa and thus inhibits blood coagulation. The molecular weight of the active enzyme is 55 kDa and the normal concentrations in human plasma is approximately 1-3 ng/mL because of the very fast turnover, the proenzyme concentration is approximately 3 μg/mL. Mutations in the Protein C gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P00745
For Use With (Application) Control
Formulation 50% water with 50% glycerol and no preservative
Gene ID (Entrez) 281428
Molecular Weight (g/mol) 58 kDa
Name Bovine Protein C
Quantity 100 μg
Source Bovine
Regulatory Status RUO
Gene Alias Activation peptide; Anticoagulant protein C; APC; autoprothrombin IIA; Blood coagulation factor XIV; EDQVDPRLIDGK; inactivator of coagulation factors Va, VIII; PC; prepro-protein C; Proc; PROC1; protein C; protein C (inactivator of coagulation factors Va and VIIIa); protein C prepropeptide; protein C, inactivator of coagulation factors Va and VIIIa; THPH3; THPH4; type I protein C; vitamin K-dependent protein C; Vitamin K-dependent protein C heavy chain; Vitamin K-dependent protein C light chain
Common Name Protein C
Gene Symbol PROC
Conjugate Unconjugated
Species Bovine
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Form Liquid
Protein Subtype Native
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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