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AdipoGen BQ-123 sodium salt
Supplier: AdipoGen AGCP30001M005
Chemical. CAS 136655-57-7. Formula C31H42N6O7 . Na. MW 609.7 . 23.0. Synthetic. Potent and selective endothelin receptor A ETA antagonist. Suppresses the ET-1-induced decrease of LPL activity. Shows protective effects in ischemic acute renal failure. Neuroprotective. Anti-hypertensive. Inhibits ET-1 receptor binding and blocks Ca2 mobilization, cellular contraction and MAP kinase activation. Cardiovascular agent. Reduces myocardial infarct size and oxidant injury. Selected Reviews.
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