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Medchemexpress LLC BQR-695 | 1513879-21-4 | 99.9% | 352.39 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1874810MM/1ML

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BQR-695 is a PI4KIIIβ inhibitor effective against both human and Plasmodium variant PI4KIIIβ. This compound is for research use only, shows no toxicity to mature red blood cells, and induces a schizont-stage arrest.

  • Has an IC50 of 80 nM for human PI4KIIIβ.
  • Has an IC50 of 3.5 nM for the Plasmodium variant of PI4KIIIβ.
  • Induces schizont-stage arrest.
  • Exhibits cross-resistance with imidazopyrazine-resistant lines.
  • Causes GFP-PHOsh2 redistribution to the parasite plasma membrane, indicating PI4P depletion.

Catalog No. 50-003-87914


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