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Cayman Chemical BradykInInhumnmouserat 10mg

Supplier: Cayman Chemical 3740810 MG
An endogenous vasodilator; binds to the bradykinin B2 receptor (IC50 = 0.54 nM in COS-7 cells expressing the human receptor) and acts as an agonist but does not bind the bradykinin B1 receptors (Ki = >10,000 nM in HEK293 cells expressing the human receptor); stimulates arachidonic acid release in CHO cells expressing the human bradykinin B2 receptor (EC50 = 0.7 nM); induces relaxation of ACh- or PDBu precontracted isolated porcine coronary arterial rings at 100 nM; induces hyperalgesia in mice at 1 UG/paw; plasma levels are increased in patients during an acute attack of angioedema
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