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Cayman Chemical BRAF InhIbItr 1hydrochLR 10mg

Supplier: Cayman Chemical 2679210 MG

A MALT1 inhibitor (IC50 5.84 M in a fluorescence assay) inhibits the growth of MALT1-dependent ABC-DLBCL cell lines (GI50s 0.2 0.5 0.4 and 0.4 M for HBL-1 TMD8 OCI-Ly3 and OCI-Ly10 cells respectively) inhibits cleavage of the MALT1 target protein CYLD in a dose-dependent manner in HBL-1 cells reduces tumor size in TMD8 and HBL-1 mouse xenograft models when administered at a dose of 25 mg/kg i.v.
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