Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Sigma Aldrich Fine Chemicals Biosciences Brain derived neurotrophic
Supplier: Sigma Aldrich Fine Chemicals Biosciences B37955UG
BDNf is a member of the neurotrophin family of growth factors that includes NGf NT-3 and NT-4. All neurotrophins have six conserved cysteine residues and share a 55% sequence identity at the amino acid level. BDNf has been shown to enhance the survival and differentiation of several classes of neurons in vitro including neural crest and placode-derived sensory neurons dopaminergic neurons in the substantia nigra basal forebrain cholinergic neurons hippocampal neurons and retinal ganglial cells.1 BDNf is expressed within peripheral ganglia and is not restricted to neuronal target fields raising the possibility that BDNf has paracrine or even autocrine actions on neurons as well as non-neuronal cells.The active form of BDNf recombinant human protein (27 kDa) is a dimer formed by two identical 119 amino acid subunits held together by strong hydrophobic interactions
Description
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?