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Apexbio Technology LLC BRD 7552 1137359-47-7 10mg
Supplier: Apexbio Technology LLC B778210
BRD 7552 is a small-molecule inducer targeting pancreatic duodenal homeobox-1 (PDX1) a transcription factor involved in pancreatic development and -cell function It is designed to enhance PDX1 expression thereby promoting -cell gene regulatory pathways BRD7552 exerts its biological activity primarily through epigenetic modulation of the PDX1 promoter region increasing both mRNA and protein expression levels In cell-based studies BRD7552 demonstrates concentration-dependent induction of insulin gene expression in human PANC-1 ductal cells and primary human islet cultures Based on these pharmacological properties BRD7552 holds research potential in studies of pancreatic cell transdifferentiation -cell function mechanisms and diabetes therapy development strategies
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