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Cayman Chemical BrexpIprazole 100mg
Supplier: Cayman Chemical 22906100 MG
A serotonin and dopamine receptor modulator; partial agonist of human 5-HT1A, D2L, and D3 receptors (EC50s = 0.49, 4.0, and 2.8 nM, respectively); antagonist of 5-HT2A, 5-HT2B, as well as α1B- and α2C-adrenergic receptors (IC50s = 6.5, 14, 0.66, and 63 nM, respectively); dose-dependently reduces conditioned avoidance response (CAR) time, inhibits apomorphine- and amphetamine-induced locomoter hyperactivity, and reverses cognitive defects in rats; antagonizes apomorphine-induced eye blinking in cynomolgus monkeys
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