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Selleck Chemical LLC Brilanestrant
Supplier: Selleck Chemical LLC S78555MG
Brilanestrant (GDC-0810 ARN-810 is a potent ER- binder (ER- IC50 6 1 nM ER- IC50 8 8 nM) a full transcriptional antagonist with no agonism and displays good potency and efficacy in ER- degradation (EC50 0 7 nM) and MCF-7 breast cancer cell viability (IC50 2 5 nM) assays with good selectivity over other nuclear hormone receptors
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