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Medchemexpress LLC Brilliant black BN | 2519-30-4 | 10 MG

Supplier: Medchemexpress LLC HY12838210MG
Brilliant black BN (E151) is an azo dye and a food colorant with potential as an antiviral agent against EV71 infection. It operates by inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A. This substance holds promise for the investigation of contagious diseases.
- Inhibits interaction between EV71 and cyclophilin A.
- Inhibits EV71-GFP infection in vitro.
- Exhibits dose-dependent inhibition of EV71-GFP in infected RD cells.
- Able to inhibit all tested 28 EV71, CVA16, and CVA6 strains.
- Shows protective effect in EV71 challenged AG129 mice in vivo.
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