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Medchemexpress LLC Brilliant blue G-250 | 6104-58-1 | 78482 | >=95.0% | 250 MG
Supplier: Medchemexpress LLC 250MGHYD0014
Brilliant Blue G-250 is a dye primarily used for visualizing proteins separated by SDS-PAGE, offering a straightforward staining procedure and high quantitation. It also functions as a safe and highly selective P2x7R antagonist, inactivating the NLRP3 inflammasome.
- Determines protein concentrations by measuring absorbance at 595 nm in the Bradford protein assay.
- Antagonist activity at human P2X7R with an IC50 of 1.37 μM in HEK293 cells.
- Anti-inflammatory activity in LPS/IFNγ-differentiated peritoneal macrophages with an IC50 of 19.77 μM.
- Anti-inflammatory activity in LPS/IFNγ-differentiated THP-1 cells with an IC50 of 19.27 μM.
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