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ION BIOSCIENCES Brilliant Lithium Assay Flex kit - 10 plates

Catalog No. NC4043215
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ION Biosciences’ Brilliant Lithium Assay Flex kit is a next-generation, fluorescence-based approach for high-throughput screening of NaV1.X channel modulators. The assay uses ION Lithium Green 1 AM (ILG-1 AM), a membrane-permeable, lithium-sensitive fluorescent dye that enables functional voltage-gated sodium channel measurements using lithium as a surrogate ion. Lithium readily permeates open NaV1.X channels while bypassing many endogenous sodium-handling mechanisms, resulting in a robust and selective readout of channel activity. Upon depolarization or pharmacological activation of NaV1.X channels, lithium accumulates intracellularly producing a rapid, quantifiable fluorescence increase that reflects real time channel activity. 10-plate kit.

Catalog No. NC4043215 Supplier ION BIOSCIENCES Supplier No. 920010
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ION Biosciences’ Brilliant Lithium Assay Flex kit is a next-generation, fluorescence-based approach for high-throughput screening of NaV1.X channel modulators. The assay uses ION Lithium Green 1 AM (ILG-1 AM), a membrane-permeable, lithium-sensitive fluorescent dye that enables functional voltage-gated sodium channel measurements using lithium as a surrogate ion. Lithium readily permeates open NaV1.X channels while bypassing many endogenous sodium-handling mechanisms, resulting in a robust and selective readout of channel activity. Upon depolarization or pharmacological activation of NaV1.X channels, lithium accumulates intracellularly producing a rapid, quantifiable fluorescence increase that reflects real time channel activity. 10-plate kit.

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