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Cayman Chemical BrInzolamIde 10mg
Supplier: Cayman Chemical 1166010 MG
A potent carbonic anhydrase inhibitor (IC50s = 3.19 and 45.3 nM for CAII and CAIV, respectively); selective for CAII and CAIV over CAI (IC50 = ~1,365 nM); reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35% in mice at 30 mg/kg; topical administration reduces intraocular pressure in a rabbit model of spontaneous ocular hypertension at 0.25, 0.5, and 1 mg/eye; reduces IOP in a cynomolgus monkey model of argon laser trabeculoplasty-induced ocular hypertension
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