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Medchemexpress LLC Brite-338733 | 503105-88-2 | 98.9% | 433.59 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY11258910MG

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BRITE-338733 is an inhibitor of E. coli RecA ATPase activity (IC50: 4.7 μM). It also inhibits the ATP hydrolysis activity of RSC chromatin remodeling enzyme by binding to its ATP-binding pocket and DNA (IC50: 0.316 μM). BRITE-338733 exhibits cytotoxicity against MCF-7 and MDA-MB-231 breast cancer cells. It can be used in studies on antibacterial adjuvants and anticancer research.

  • Exhibits strong and stable binding affinity for the ATPase domain of Sth1, the catalytic subunit of the yeast RSC complex.
  • Potently inhibits the ATP hydrolysis activity of purified yeast RSC complex.
  • Exhibits cytotoxicity against human breast cancer cell lines MCF-7 and MDA-MB-231.

Catalog No. 50-004-36122


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