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Medchemexpress LLC BRITE-338733 | 503105-88-2 | 98.9% | 433.59 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY112589100MG

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BRITE-338733 is an inhibitor of E. coli RecA ATPase activity (IC50: 4.7 μM) and also inhibits the ATP hydrolysis activity of RSC chromatin remodeling enzyme by binding to its ATP-binding pocket and DNA (IC50: 0.316 μM). It exhibits cytotoxicity against MCF-7 and MDA-MB-231 breast cancer cells and can be used in studies on antibacterial adjuvants and anticancer research.

  • Inhibits E. coli RecA ATPase activity.
  • Inhibits ATP hydrolysis activity of RSC chromatin remodeling enzyme.
  • Exhibits cytotoxicity against breast cancer cells (MCF-7 and MDA-MB-231).
  • Useful for studies on antibacterial adjuvants and anticancer research.
  • Shows strong and stable binding affinity for the ATPase domain of Sth1.
  • Potently inhibits ATP hydrolysis activity of purified yeast RSC complex.

Catalog No. 50-004-36535


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