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Medchemexpress LLC BRL-44408 maleate | 681806-46-2 | 99.0% | 10 MG
Supplier: Medchemexpress LLC HY12716A10MG
BRL-44408 maleate is a selective, blood-brain barrier-permeable α2A-adrenergic receptor antagonist with a Kᵢ value of 8.56 nM against human targets. It exhibits antidepressant and analgesic effects, and attenuates sepsis-induced acute lung injury by regulating neurotransmitter release or inhibiting signaling pathways. It can be used in studies related to acute respiratory distress syndrome, depression, and visceral pain.
- Selective α2A-adrenergic receptor antagonist
- Blood-brain barrier permeable
- Exhibits antidepressant and analgesic effects
- Attenuates sepsis-induced acute lung injury
- Regulates neurotransmitter release and inhibits signaling pathways
- Used in studies for acute respiratory distress syndrome, depression, and visceral pain
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