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Medchemexpress LLC Brm/Brg1 ATP inhibitor-1 | 2270879-17-7 | 99.7% | 10 MG
Supplier: Medchemexpress LLC HY11937410MG
BRM/BRG1 ATP inhibitor-1 is an orally active, allosteric small-molecule inhibitor that selectively targets the ATPase activity of BRM (SMARCA2) and BRG1 (SMARCA4). It demonstrates sub-nanomolar potency and has shown anticancer activity in preclinical studies, making it useful for epigenetic and chromatin remodeling research.
- Potent allosteric dual inhibitor of BRM and BRG1 ATPase activity.
- Sub-nanomolar potency (IC50 < 0.005 μM) for both targets.
- High purity suitable for biochemical and cell-based assays.
- Available in solid and solution formats, including 10 mg solid and 10 mM in DMSO.
- Recommended storage conditions preserve stability (powder: -20°C; in solvent: -80°C).
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