Sigma Aldrich Bromotripyrrolidinophosphonium Hexafluorophosphate

Catalog No.	Quantity
18-565-5G	5 g
18-565-1G	1 g
18-565-25G	25 g

Catalog No. 18-565-5G Supplier Sigma Aldrich Supplier No. 185655G

Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

It can be used as a coupling reagent:For Suzuki-Miyaura cross-coupling of phenols and arylboronic acids to synthesize biaryls and heterobiaryls.To functionalize pyrimidines (synthesized from 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) via the Kappe dehydrogenation) by using various nucleophiles.To synthesize formamidines by coupling with various primary amines and N,N-diisopropylethylamine.It can also be used as an activating reagent:For the activation of C-OH bond in tautomerizable heterocycles to form the phosphonium salt which aids the Sonogashira coupling of heterocycles with various alkynes.For the one-pot activation of C-O bond in phenols and further coupling reaction with phosphine oxide or phosphite to form C-P bonds.Reactive peptide coupling reagent suitable for +a,+a-dialkyl amino acids; Synthesis of depsipeptidesPyBroP is a registered trademark of Merck KGaA, Darmstadt, Germany

Specifications

• CAS: 132705-51-2
• Molecular Formula: C12H24BrF6N3P2
• Linear Formula: C12H24BrF6N3P2
• MDL Number: MFCD00077412
• Quantity: 5 g
• Synonym: PyBroP(R)
• Molecular Weight (g/mol): 466.18 g/mol