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Medchemexpress LLC Bronopol | 52-51-7 | 98.0% | 100 G
Supplier: Medchemexpress LLC HYB1217100G
Bronopol is an antibacterial agent effective against Gram-negative bacteria. It functions by oxidizing protein thiols, inhibiting enzymatic activity, and acting as a formaldehyde releaser. In vitro, it activates THP-1 cells, increases CD86 expression, induces IL-8 secretion, and promotes early expression of HMOX1 and HSPA6 genes. In vivo, it can induce chemical peritonitis and transitory pain aggressive behavior in Sprague-Dawley rat models.
- Antibacterial agent with low toxicity to mammals
- Effective against Gram-negative bacteria
- Oxidizes protein thiols and inhibits enzymatic activity
- Acts as a formaldehyde releaser
- Activates THP-1 cells and increases CD86 expression in vitro
- Induces IL-8 secretion and promotes gene expression in vitro
- Can induce chemical peritonitis and pain in Sprague-Dawley rat models in vivo
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