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Cayman Chemical BryostatIn 1 10ug
SDP

Supplier:  Cayman Chemical 1480210 UG

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A marine macrolide with diverse biological activities; binds to PKCα, PKCβ1, PKCγ, PKCδ, PKCε, PKCη, and PKCθ (Kis = 0.8-3.0 nM); induces PKC activation or inhibition in cancer cells in a concentration-dependent manner; reduces the production of IL-2 and increases the production of IL-10 in LPS-stimulated mouse BMDCs at 50 nM; decreases cell surface levels of CD4 and CCR5 and reduces HIV-1 infectivity in isolated human monocyte-derived macrophages; reduces spinal cord and brain T cell infiltration and disease severity in a mouse model of EAE at 30 UG/kg; decreases blast-induced increases in BBB permeability in a rat model of TBI at 2.5 mg/kg

Catalog No. 50-297-2277


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