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Medchemexpress LLC BSJ-03-123 | 2361493-16-3 | 99.19% | 937.01 | 10 MG
Supplier: Medchemexpress LLC HY111556100MG
BSJ-03-123 is a PROTAC connected by ligands for Cereblon and CDK, functioning as a potent and novel CDK6-selective small-molecule degrader. It causes a pronounced anti-proliferative effect in CDK6-dependent AML cell lines by inducing a G1 cell-cycle arrest without a measurable increase in apoptosis.
- Potent and novel CDK6-selective small-molecule degrader
- Induces G1 cell-cycle arrest in AML cell lines
- Causes anti-proliferative effect in CDK6-dependent AML cell lines
- Does not significantly increase apoptosis
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