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Medchemexpress LLC BSJ-04-122 | 2513289-74-0 | C15H12ClN5O | 5 MG
Supplier: Medchemexpress LLC HY1521855MG
BSJ-04-122 is a highly potent covalent dual inhibitor targeting MKK4 and MKK7, key kinases involved in cellular signaling pathways. It demonstrates strong inhibitory activity against MKK4 with an IC50 value of 4 nM and against MKK7 with an IC50 value of 181 nM. This compound is primarily utilized in cancer research, exhibiting its ability to induce a robust reduction in JNK phosphorylation.
- Potent covalent dual inhibitor of MKK4 and MKK7
- Inhibits MKK4 with an IC50 of 4 nM
- Inhibits MKK7 with an IC50 of 181 nM
- Induces robust reduction in JNK phosphorylation
- Enhances antiproliferative effects when combined with JNK-IN-8
- Useful for cancer research applications
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