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Apexbio Technology LLC Bufalin 465-21-4 20mg
Supplier: Apexbio Technology LLC N150720
Bufalin (CAS 465-21-4) is a cardiotonic steroid compound originally derived from the venom of the Chinese toad It exerts its biological effects by modulating intracellular signaling pathways notably by inducing apoptosis and promoting cell differentiation in human monocytic U-937 cells Mechanistic studies suggest that Bufalin activates the AP-1 transcription factor via a mitogen-mediated pathway contributing to its observed effects on cell fate Due to these properties Bufalin is employed in biomedical research to investigate mechanisms of apoptosis cell differentiation and the role of steroidal compounds in cellular signaling pathways
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