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Cayman Chemical Buflomedil (hydrochloride), Purity: ≥95%, CAS: 35543-24-9, 5 g
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Catalog No. 502991468
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An α-AR antagonist and vasoactive compound; binds to rat α1A- and α1B-ARs (Kis = 4.06 and 6.84 µM, respectively) and human platelet α2-ARs (IC50 = 1 µM); inhibits phenylephrine-, clonidine-, sypathetic nerve stimulation-, or norepinephrine-induced contration of isolated canine saphenous veins from 0.06-60 µM; inhibits ADP-, collagen-, or epinephrine-induced aggregation of isolated human platelets at 100 µM; reduces hippocampal neuronal cell death in a rat model of carotid clamping-induced ischemia-reperfusion injury at 10 mg/kg

Catalog No. 50-299-1468 Supplier Cayman Chemical Supplier No. 311845 G
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An α-AR antagonist and vasoactive compound; binds to rat α1A- and α1B-ARs (Kis = 4.06 and 6.84 µM, respectively) and human platelet α2-ARs (IC50 = 1 µM); inhibits phenylephrine-, clonidine-, sypathetic nerve stimulation-, or norepinephrine-induced contration of isolated canine saphenous veins from 0.06-60 µM; inhibits ADP-, collagen-, or epinephrine-induced aggregation of isolated human platelets at 100 µM; reduces hippocampal neuronal cell death in a rat model of carotid clamping-induced ischemia-reperfusion injury at 10 mg/kg

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