Bumetanide, 98+%

Description

Inhibitor of the sodium-potassium-chloride cotransporter | CAS: 28395-03-1 | C17H20N2O5S | 364.416 g/mol

Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1

Solubility
Soluble in ethanol (10 mg/ml), DMSO (25 mg/ml), acetone, benzene, methanol, propylene glycol, and water (<1mg/mL).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from acids.

Specifications

Chemical Identifiers

• CAS: 28395-03-1
• Molecular Formula: C17H20N2O5S
• Molecular Weight (g/mol): 364.416
• MDL Number: MFCD00078949
• InChI Key: MAEIEVLCKWDQJH-UHFFFAOYSA-N
• Synonym: bumetanide, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, bumex, burinex, fordiuran, lunetoron, fontego, segurex, bumetanida, bumetanidum
• PubChem CID: 2471
• ChEBI: CHEBI:3213
• IUPAC Name: 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
• SMILES: CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2

• Melting Point: 230°C to 231°C
• Color: White
• Quantity: 1 g
• Merck Index: 14,1484
• Solubility Information: Soluble in ethanol (10mg/ml),DMSO (25mg/ml),acetone,benzene,methanol,propylene glycol,and water (<1mg/ml).
• Formula Weight: 364.4
• Percent Purity: ≥98%
• Physical Form: Solid
• Chemical Name or Material: Bumetanide

Safety and Handling

EINECSNumber	249-004-6
RTECSNumber	DG4910000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only