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Bumetanide, 98+%

Catalog No. AAJ6230203
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Catalog No. AAJ6230203 Supplier Thermo Scientific Chemicals Supplier No. J6230203
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Description

Inhibitor of the sodium-potassium-chloride cotransporter | CAS: 28395-03-1 | C17H20N2O5S | 364.416 g/mol

Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1

Solubility
Soluble in ethanol (10 mg/ml), DMSO (25 mg/ml), acetone, benzene, methanol, propylene glycol, and water (<1mg/mL).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from acids.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 28395-03-1
Molecular Formula C17H20N2O5S
Molecular Weight (g/mol) 364.416
MDL Number MFCD00078949
InChI Key MAEIEVLCKWDQJH-UHFFFAOYSA-N
Synonym bumetanide, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, bumex, burinex, fordiuran, lunetoron, fontego, segurex, bumetanida, bumetanidum
PubChem CID 2471
ChEBI CHEBI:3213
IUPAC Name 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
SMILES CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2

Specifications

Melting Point 230°C to 231°C
Color White
Quantity 1 g
Merck Index 14,1484
Solubility Information Soluble in ethanol (10mg/ml),DMSO (25mg/ml),acetone,benzene,methanol,propylene glycol,and water (<1mg/ml).
Formula Weight 364.4
Percent Purity ≥98%
Physical Form Solid
Chemical Name or Material Bumetanide

Safety and Handling

EINECSNumber 249-004-6
RTECSNumber DG4910000
TSCA No
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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