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Medchemexpress LLC α-Bungarotoxin | 11032-79-4 | 99.0% | 7984.12 | 1 MG
Supplier: Medchemexpress LLC HYP12641MG
α-Bungarotoxin is a potent competitive antagonist at nicotinic acetylcholine receptors (nAChRs). It acts as a selective α7 receptor blocker, inhibiting α7 currents with an IC50 of 1.6 nM while showing no effect on α3β4 currents at concentrations up to 3 μM. This toxin binds specifically and with high affinity to the nicotinic acetylcholine receptor, competing with natural ligands and acting as a powerful inhibitor of its function, resulting in functional blockade of AcChoRs at the neuromuscular junction.
- Competitive antagonist at nicotinic acetylcholine receptors
- Selective α7 receptor blocker
- Inhibits α7 currents with an IC50 of 1.6 nM
- Binds specifically and with high affinity to the nicotinic acetylcholine receptor
- Competes with natural ligand binding
- Potent competitive inhibitor of nicotinic acetylcholine receptor function
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