Medchemexpress LLC Buspirone hydrochloride | 33386-08-2 | 99.99% | 1 ML

Supplier:  Medchemexpress LLC HYB111510MM/1ML

Buspirone hydrochloride is a 5-HT1A receptor agonist. It can be used for anxiety and depression research.

• 5-HT1A receptor agonist
• Can be used for anxiety and depression research
• Has cytotoxic effect in lymphocytes (0-400 μg/mL; 6 hours)
• Induces ROS formation, MMP collapse, lipid peroxidation, lysosomal damage and elevation of glutathione disulfide (GSSG) (0-180 μg/mL; 0-3 hours; lymphocytes)
• Reduces anxiety/depression behaviors in C57BL/6N mice (1-5 mg/kg; i.p. and i.g.; for 5 days)
• Restores IS-shifted β-diversity in the gut microbiota in C57BL/6N mice (1-5 mg/kg; i.p. and i.g.; for 5 days)
• Reduces TNF-α expression and NF-κB+/Iba1+ cell population in the hippocampus and myeloperoxidase activity and NF-κB+/CD11c+ cell population in the colon in C57BL/6N mice
• Reduces the IS- or EC-induced gut proteobacteria population in C57BL/6N mice

Catalog No. 50-004-11322