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STEMCELL Technologies Busulfan, Size: 100 g

Supplier: STEMCELL Technologies 1001125

Inhibit proliferation of cancer cells by creating DNA breaks and DNA crosslinks with busulfan (Iwamoto et al.). Highly potent and cell-permeable busulfan forms interstrand crosslinks between the DNA bases guanine and adenine and between guanine and guanine (Ponti et al.). DNA breakage induced by busulfan-mediated DNA crosslinking induces senescence in cells (Chen et al.).
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