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Medchemexpress LLC Butanedioic acid, 1-(2,2-dimethylhydrazide) | 1596-84-5 | 99.8% | 160.17 | 1 ML
Supplier: Medchemexpress LLC HY1364310MM/1ML
Daminozide is a plant growth regulator that functions as a selective inhibitor of human KDM2/7 histone demethylases. It exhibits IC50 values of 0.55, 1.5, and 2.1 μM for PHF8, KDM2A, and KIAA1718, respectively, and demonstrates over 100-fold selectivity for the KDM2/7 subfamily compared to other demethylase subfamily members.
- Selective inhibitor of human KDM2/7 histone demethylases
- IC50s of 0.55, 1.5, and 2.1 μM for PHF8, KDM2A, and KIAA1718
- Greater than 100-fold selectivity for KDM2/7 subfamily
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