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Medchemexpress LLC Butanoic acid, 3-oxo-, sodium salt (1:1) | 623-58-5 | 98.0% | 124.07 | 50 MG
Supplier: Medchemexpress LLC HY112540B50MG
Acetoacetic acid sodium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. It can be used to study metabolic diseases. The sodium salt form of the compound is prone to thermal instability.
- Induces oxidative stress by decreasing mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px)
- Increases MDA content
- Inhibits very low density lipoprotein (VLDL) assembly
- Downregulates apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR)
- Leads to triglyceride (TG) accumulation in hepatocytes
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