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Medchemexpress LLC Butanoic acid, 4-(dimethylamino)-, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien... | 1224606-06-7 | 99.9% | 642.09 | 500 MG
SDP

Supplier:  Medchemexpress LLC HY112251500MG

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D-Lin-MC3-DMA is an ionizable cationic lipid that serves as a potent siRNA delivery vehicle. It is intended for research use only and not for sale to patients.

  • Potent siRNA delivery vehicle.
  • Exhibits an optimized pKa value that leads to dramatically enhanced potency in vivo when formulated in lipid nanoparticles (LNPs) for siRNA delivery.
  • Can be formulated into lipid nanoparticles with specific molar ratios for siRNA targeting transthyretin (TTR) mRNA.
  • LNP-siRNA systems containing D-Lin-MC3-DMA optimize gene silencing potency in hepatocytes following IV administration in mice.
  • Available in various quantities and solution formats.

Catalog No. 50-004-38340


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