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STEMCELL Technologies Butein, Size: 10 mg
SDP

Supplier:  STEMCELL Technologies 73464

Encompass

Inhibit nuclear factor (NF)-κB and prevent phosphorylation and degradation of TNF-dependent IκBα with Butein (Yang et al. Biochem Biophys Res Commun, 1998; Pandey et al. J Biol Chem, 2007; Orlikova et al. Oncol Rep, 2012). This plant polyphenol is used in cancer research to inhibit various processes, such as the TNF-α-induced invasion of human lung adenocarcinoma H1299 cells (Pandey et al. J Biol Chem, 2007); growth in human hepatoma cancer cell lines HepG2 and Hep3B (Moon et al. Cancer Lett, 2010); and testosterone-induced proliferation in breast cancer cells (Wang et al. Life Sci, 2005). Butein also exhibits anti-inflammatory properties in a mouse macrophage cell line by inhibiting LPS-induced expression of iNOS (Lee et al. Biochem Biophys Res Commun, 2004). Butein is supplied as a crystalline solid with ≥95% purity; Molecular weight 272.3 g/mol; CAS Number 487-52-5. Visit STEMCELL.com for more information and related products.

Catalog No. 50-197-6082


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