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Cayman Chemical ButyrylLcarnItInchLRIde 50mg

Supplier: Cayman Chemical 2654250 MG

An inhibitor of Eg5 inhibits the basal and microtubule-stimulated states (IC50s 1000 and 140 nM respectively) selective over nine other human kinesins reversibly inhibits Eg5-driven microtubule sliding velocity (IC50 500 nM) induces cell cycle arrest in HeLa cells (IC50 700 nM) reversibly halts the cell cycle in the mitotic phase inhibits cancer cell growth in the NCI 60 human cancer cell line panel (average GI50 1.3 UM) and in mouse xenograft models
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