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Biolegend Brilliant Violet 605 Anti-Human CD25 Antibody | 100 Tests
Supplier: Biolegend 356142
CD25 is a 55 kD type I transmembrane glycoprotein also known as low affinity IL-2 receptor α chain or Tac. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses. CD25 associates with IL-2 receptor Beta (CD122) and common Y (CD132) chains to form a high affinity IL-2R complex.
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