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Medchemexpress LLC BX517 | 850717-64-5 | 98.0% | 282.30 | 100 MG
Supplier: Medchemexpress LLC HY13842100MG
BX517 is a potent and selective inhibitor of PDK1, demonstrating an IC50 of 6 nM. It effectively blocks the activation of Akt in various tumor cells with submicromolar potency. This compound exhibits significant selectivity, being at least 100-fold more selective against PDK1 compared to a panel of seven other Ser/Thr and Tyr kinases.
- Potent and selective inhibitor of PDK1
- Blocks activation of Akt in tumor cells
- Exhibits submicromolar potency
- Highly selective against other Ser/Thr and Tyr kinases
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