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Enzo Life Sciences BX795 (10mg). CAS: 702675-74-9
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Supplier:  Enzo Life Sciences ENZCHM1890010

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BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC50 = 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-ε. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of interferon regulatory factor 3. BX795 also is a potent inhibitor of cell growth of multiple cancer cell lines with IC50 values ranging from submicromolar amounts (0.368 µM to greater than 450 µM). Alternative name: N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide. Purity: ≥97% (HPLC). Solubility: Soluble in DMSO (118mg/ml) or ethanol (1mg/ml). Long Term Storage: -20°C.

Catalog No. 50-201-3503


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