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Cayman Chemical BYK 191023hydrochlorIde 50mg
SDP

Supplier:  Cayman Chemical 1317750 MG

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A selective iNOS inhibitor (IC50s = 0.086, 17, and 162 μM for human recombinant iNOS, nNOS, and eNOS, respectively); inhibits iNOS-induced nitrite generation in RMC, RAW, and HEK293 cells (IC50s = 33, 3.1, and 13 μM, respectively); suppresses LPS-induced increases in plasma nitrate and nitrite levels in rats (ED50 = 14.9 μmol/kg per hour); prevents development of delayed hypotension in a rat model of LPS-induced endotoxemia at 50 μmol/kg per hour; increases mean arterial pressure and renal blood flow in a sheep model of septic shock

Catalog No. 50-295-1744


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