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Bachem Bz-Nle-Lys-Arg-Arg-AMC

Supplier: Bachem 4055312.0001

Bz-Nle-Lys-Arg-Arg-AMC Trifluoroacetate, 863975-32-0, C41H60N12O7, Mr 833.00, 1mg. Substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. The kcat/Km value of Bz-NleKRR-AMC for the dengue virus type 4 (DEN4) enzyme is > 800 fold higher than that of Boc-Gly-Arg-Arg-AMC, a widely used NS3 substrate (kcat = 2.9 s-1, Km = 8.6 μM for DEN4). For yellow fever virus NS3 protease the kcat value was 0.111 s-1, the Km value 14.6 μM.
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