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  8. C 646, Tocris Bioscience™

C 646, Tocris Bioscience™

Catalog No. 420010
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective p300/CBP inhibitor

Selective p300/CREB-binding protein (CBP) inhibitor (Ki = 400 nM). Selective for p300 over six other histone acetyltransferases (HATs). Suppresses histone H3 and H4 acetylation in mouse fibroblast cell lines.

This compound is a mixture of Z:E isomers (∽ 80:20).

Chemical Identifiers

CAS 328968-36-1
Molecular Formula C24H19N3O6
Molecular Weight (g/mol) 445.43
MDL Number MFCD01784780
InChI Key HEKJYZZSCQBJGB-UHFFFAOYSA-N
Synonym 4-4-5-4,5-dimethyl-2-nitrophenyl furan-2-yl methylidene-3-methyl-5-oxopyrazol-1-yl benzoic acid
PubChem CID 2871948
IUPAC Name 4-(4-{[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene}-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
SMILES CC1=NN(C(=O)C1=CC1=CC=C(O1)C1=CC(C)=C(C)C=C1[N+]([O-])=O)C1=CC=C(C=C1)C(O)=O

Specifications

Quantity 10 mg
Formula Weight 445.42
Percent Purity >98%
Chemical Name or Material C 646

Safety and Handling

Recommended Storage Store at +4°C
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