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AdipoGen C12-DL-HSL
SDP

Supplier:  AdipoGen CDXD0339M010

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Chemical. CAS 18627-38-8. Formula C16H29NO3. MW 283.4. Synthetic. N-Dodecanoyl-DL-homoserine lactone C12-HSL is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta IL-1beta and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte HaCaT cells. It also was shown to induce cell death by apoptosis.

Catalog No. 50-256-1102


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