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Medchemexpress LLC C21H18F7N3O4 | 98.0% | 509.37 | 1 MG
SDP

Catalog No. 5000392896
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RTx-161 is an allosteric Polθ polymerase inhibitor with an IC50 value of 4.1 nM. It selectively kills HR-deficient cancer cells and suppresses PARP inhibitor (PARPi) resistance in multiple genetic backgrounds, including HR-proficient cells. RTx-161 can also induce apoptosis.

  • Allosteric Polθ polymerase inhibitor with an IC50 of 4.1 nM.
  • Selectively kills HR-deficient cancer cells.
  • Suppresses PARP inhibitor (PARPi) resistance in multiple genetic backgrounds, including HR-proficient cells.
  • Can induce apoptosis.

Catalog No. 50-003-92896 Supplier Medchemexpress LLC Supplier No. HY1614301MG
May include imposed supplier surcharges.
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RTx-161 is an allosteric Polθ polymerase inhibitor with an IC50 value of 4.1 nM. It selectively kills HR-deficient cancer cells and suppresses PARP inhibitor (PARPi) resistance in multiple genetic backgrounds, including HR-proficient cells. RTx-161 can also induce apoptosis.

  • Allosteric Polθ polymerase inhibitor with an IC50 of 4.1 nM.
  • Selectively kills HR-deficient cancer cells.
  • Suppresses PARP inhibitor (PARPi) resistance in multiple genetic backgrounds, including HR-proficient cells.
  • Can induce apoptosis.

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