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Medchemexpress LLC C49H64ClFN10O7S | 3034244-71-5 | 99.2% | 991.61 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1616335MG

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PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC50 <100 nM. It binds CRBN-DDB1 with a Ki of 36 nM. This compound degrades EGFR, focal adhesion kinase (FAK), and RSK1, and inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM. This product is for research use only and is not sold to patients.

  • PROTAC degrader for epidermal growth factor receptor (EGFR).
  • Exhibits a DC50 <100 nM.
  • Binds CRBN-DDB1 with a Ki of 36 nM.
  • Degrades epidermal growth factor receptor, focal adhesion kinase (FAK), and RSK1.
  • Inhibits the proliferation of BaF3 wild type and EGFR mutants with an IC50 <100 nM.
  • Intended for research use only.

Catalog No. 50-003-91819


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